Vyvanse is a prescription stimulant drug commonly used to treat ADD/ADHD In adults and children. How long Vyvanse remains in a person’s system depends on a variety of factors. The half-life of Vyvanse (the amount of time it takes for half of the dose of the drug to be purged from the system) is less than one hour. Several tests can detect Vyvanse’s presence, but the one used most often is a urinalysis, which can identify the drug’s presence for up to three days.
Duration of Effects
The drug lisdexamfetamine is a prodrug of dextroamphetamine. As such, Vyvanse must be metabolized into dextroamphetamine for it to enact effects. Vyvanse is broken down by red blood cells and excreted through urine.
Like Adderall or methamphetamine, Vyvanse works by increasing activity in the central nervous system (CNS). This action can make the individual feel more alert, attentive, and energetic. How long the effects of Vyvanse persist largely depends on the size of the dose that is used. Vyvanse, as a prodrug, must be broken down by the body before it will start to work. Once metabolized, the effects can last up to 12 hours.
Once a drug enters a person’s system and reaches its peak levels in the blood, the half-life is the amount of time needed for the concentration of the drug to be halved. The half-life of Vyvanse is based on the active ingredient lisdexamfetamine, which, as noted, has a half-life of less than an hour. It is eventually converted to dextroamphetamine, which has a much longer half-life of around 12 hours.
Vyvanse can be administered in several different doses: 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, or 70 mg. The dose will not affect the half-life of the drug itself but will affect the total duration of time the drug remains in a person’s system.
Vyvanse Drug Test Detection Time
How long Vyvanse can be identified on a drug screen depends on the method of testing. Conventional drug testing methods include urine, saliva, blood, and hair follicle screenings.
Urine – Vyvanse can be found in a urine test for up to three days after the last use.
Saliva – Saliva tests are often used because drug levels are usually similar or higher than those detected in blood, and they are much less invasive. Vyvanse will test positive on a saliva drug screen for up to 48 hours after the last use.
Blood – How long Vyvanse can be identified in the blood depends greatly on its half-life, which is relatively short. Vyvanse will only be detectable on a blood test for about 8 hours following use.
Hair – A hair follicle test is sometimes used to detect the presence of drugs for much longer than which other methods are capable. For example, Vyvanse use can be revealed on a hair drug test for up to 90 days after the last use.
Factors Influencing How Long Vyvanse Remains in a Person’s System
Frequency and amount of use – How long Vyvanse stays in the system depends on the amount and frequency at which it is taken. It can be prescribed from anywhere between 30–70 mg per day to treat ADD/ADHD. Using a higher dose or using it more often will increase the time needed for it to be eliminated from an individual’s system.
User health and activity levels – In general, drugs are metabolized faster in people who are healthier and more active. Exercising can affect an individual’s basal metabolic rate (the rate of metabolism at rest), which also affects the time need to break down substances. A person’s overall health can also influence the rate at which Vyvanse is metabolized. Vyvanse metabolites are excreted in the urine, so those with kidney issues may take longer to eliminate it from their system.
Method of administration – Vyvanse can be consumed orally in pill form, by chewing a tablet, or by opening the capsule and mixing it into a liquid or yogurt. All of these routes of use should facilitate a similar delivery of the drug if taken as prescribed.
Presence of other drugs or alcohol – The duration of time needed to eliminate Vyvanse from a person’s system can also depend on if he or she is using other substances. The metabolic rate of Vyvanse can be impacted by several other prescription drugs, including MAOI and tricyclic antidepressants, which tend to increase the drug’s bioavailability.
Getting Help for Addiction
Vyvanse is a potentially addictive substance that can be dangerous if abused. Just Believe Detox and Just Believe Recovery can help if you or a loved one are struggling with a substance use disorder. To learn more about detox services or our comprehensive, research-based treatment programs, please contact us now to discover how we help those in need to break the cycle of addiction for life!