Trintellix (vortioxetine) is an SSRI (selective serotonin reuptake inhibitor) available in tablet form designed for oral use. Drinking alcohol while using Trintellix is not advised and may exacerbate drug side effects, such as dizziness and vomiting. It may also increase depressive symptoms and undermine the medication’s effectiveness.
What Is Trentellix?
Trintellix is an antidepressant that works by balancing serotonin levels in the brain. Serotonin is, in part, responsible for feelings of well-being and reward. Individuals who require mood stabilization in this way may experience improved mood, sleep, appetite, and energy levels.
Trentellix and its generic equivalents are available by prescription only. It comes in the form of a small tablet ingested orally once daily, ideally around mealtime. While using this medication, individuals may notice some improvement in mood and physical symptoms in just a few days. However, it can take several weeks to experience the drug’s full therapeutic effects.
Combining Trentellix and Alcohol
Alcohol is a potentially dangerous central nervous system (CNS) depressant that can adversely affect a person’s mood and sabotage the efficacy of an antidepressant. For this reason and others, drinking alcohol with any drug in this class is not recommended by doctors.
Unfortunately, because SSRIs are among the most commonly used antidepressants, mixing them with alcohol use for many may be routine. However, the Food and Drug Administration (FDA) cautions against combining antidepressants and alcohol because both substances affect brain neurochemicals vitally needed for mood regulation.
As noted, SSRIs, such as Paxil, Zoloft, Prozac, and Trentellix, work by regulating serotonin’s activity, and conversely, alcohol interferes with the function of numerous brain receptors, including gamma-aminobutyric acid (GABA), serotonin, and dopamine. For this reason and others, it has a high potential to alter behavior and mood adversely.
Alcohol’s action can ultimately undermine Trentellix’s primary medical purpose. And, unfortunately, many individuals suffering from a mood disorder may be more likely to combine their medication with other substances such as alcohol in a misguided attempt to enhance pleasurable feelings.
People who take SSRIs and drink alcohol may experience suicidal ideations, dizziness, nausea and vomiting, intense anxiety, headaches, digestive problems, and impaired motor coordination. Also, the effects of consuming alcohol, such as impaired judgment and motor skills and slurred speech, can become more pronounced when using antidepressants.
Because interactions that may occur between Trentellix and alcohol can be severe, unpredictable, and dangerous in some instances, it is highly recommended that those who use this medication limit their alcohol intake or abstain entirely.
Why You Should Not Combine Trentellix and Alcohol
If you have been prescribed Trentellix to address a mood disorder such as depression, you should avoid using other substances that could reduce the medication’s effectiveness. SSRIs work to manage serotonin levels in the brain, and alcohol, in turn, conversely affects brain function and mood, often worsening symptoms of depression and anxiety.
Therefore, decreasing or abstaining from alcohol consumption may be instrumental in allowing the SSRI in your system to do its job as intended. Some people who take Trentellix and consume excessive amounts of alcohol can experience blackouts or memory lapses, which can place them and those around them at a higher risk of injury.
Signs and Symptoms of Overdose
Overdosing on an antidepressant medication is possible if an individual takes an excessive amount. However, a person is more likely to overdose if the medication is mixed with alcohol or other prescription or illicit drugs, especially those that depress the central nervous system.
People can experience varying symptoms related to CNS depression or depressant overdose. Primary factors that affect the effects of CNS depression include the type and dose of the substance(s) used. Mild symptoms of CNS depression may consist of the following:
- Loss of motor coordination
- Muscle weakness
- Dizziness and disorientation
- Slurred speech or stuttering
- Shortness of breath
- Reduced heart rate
- Dry mouth
- Blurry or double vision
Symptoms of severe CNS depression include:
- Perilously slow heart rate
- Profound low respiration
- Extreme confusion
- Memory loss
- Uncontrollable vomiting
- Severely impaired judgment
- Blue lips or fingertips
- Cold, clammy skin
- Intense mood swings
- Very slow reflexes
If an individual is experiencing any of these symptoms, they should seek immediate medical intervention. Ultimately, severe symptoms can result in unresponsiveness, coma, and death.
Treatment for Alcohol Abuse
If you are using an SSRI such as Trentellix for depression or another mental health disorder, drinking alcohol can compromise the medication’s effectiveness and lead to unwanted psychological and physical health complications. As such, those struggling to restrict their alcohol intake due to addiction should seek professional substance abuse treatment as soon as possible.
Just Believe Detox and Just Believe Recovery programs feature a multifaceted approach to treating addiction and any co-occurring conditions, such as depression and anxiety. Our programs include a wide variety of clinically-proven, therapeutic services, such as psychotherapy, individual and group counseling, group support, substance abuse education, health and wellness education, mindfulness therapy, aftercare planning, and more.